Wednesday, August 31, 2016

ESC: Medical Therapy Adequate for Plaque Erosion

(MedPage Today) -- Pilot study suggests stenting not needed in uncomplicated cases
via ESC: Medical Therapy Adequate for Plaque Erosion
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ESC: Effient and Brilinta Equal for Post-MI Prevention

(MedPage Today) -- PRAGUE-18 trial underpowered but enough to prove no big difference
via ESC: Effient and Brilinta Equal for Post-MI Prevention
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Why is Cardiovascular Drug Development Sagging?

(MedPage Today) -- CV disease remains No. 1 killer, yet pharma is pulling back
via Why is Cardiovascular Drug Development Sagging?
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ESC: Savaysa Safe for Afib Cardioversion

(MedPage Today) -- ENSURE-AF trial finds similarity to standard anticoagulant regimen
via ESC: Savaysa Safe for Afib Cardioversion
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Tuesday, August 30, 2016

ESC: Coronary CT Prescreen Saves Big $$

(MedPage Today) -- Subsequent patients outcomes on par with invasive coronary angiography
via ESC: Coronary CT Prescreen Saves Big $$
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ESC: Apheresis Eases Refractory Angina

(MedPage Today) -- Small sham-controlled trial promising for symptoms and perfusion
via ESC: Apheresis Eases Refractory Angina
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Cancer Patients With Afib Tolerate NOAC (CME/CE)

(MedPage Today) -- Bleeding risk and mortality higher than general population but anticoagulation still works
via Cancer Patients With Afib Tolerate NOAC (CME/CE)
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Make the Diagnosis: Puzzling Palpitations

(MedPage Today) -- Case Findings: A 44-year-old male presents with palpitations of 3 months' duration. At first they were occasional and occurred about twice a week. However, they have increased over time with frequency up almost hourly. He has noticed a recent 10-pound weight gain, increased lower extremity swelling, and inability to lie flat. He denies any fevers or chills. His last exercise stress test 5 months ago was normal. His current medications include metoprolol 12.5 mg twice daily, lisinopril 10 mg daily, aspirin 81 mg daily, furosemide 40 mg daily. There have been no recent readjustments in his medical regimen. BP in the clinic on presentation was 110/80 mm Hg, HR 60/min, and the patient was in no acute distress. JVD is elevated, with bilateral basal pulmonary crackles and bilateral lower extremity pitting edema. No heart murmurs are apparent on examination. No baseline is available. Blood work reveals Hemoglobin 14 mg/dl, Creatinine 1.4 mg/dL and BNP 5000. The clinician obtains a Transthoracic Echocardiogram that shows an ejection fraction of 30% with no significant valvular pathology. The patient's ECG is shown below. What is causing the patient's cardiomyopathy?
via Make the Diagnosis: Puzzling Palpitations
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ESC: Longer Cardiac Rehab Not Better? (CME/CE)

(MedPage Today) -- No improvement in risk factors overall, but some help for motivated patients
via ESC: Longer Cardiac Rehab Not Better? (CME/CE)
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ESC: PCSK9 Tx -- Ready for Prime Time or Still Unproven?

(MedPage Today) -- Debate highlights pros and cons of these cholesterol-lowering drugs
via ESC: PCSK9 Tx -- Ready for Prime Time or Still Unproven?
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ESC: DES or BMS? No Mortality Difference

(MedPage Today) -- After 6 years, death was as likely in DES patients as in BMS patients
via ESC: DES or BMS? No Mortality Difference
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Monday, August 29, 2016

ESC: PCSK9 Drug Dramatically Cuts Apheresis in FH

(MedPage Today) -- Frequency dropped 75% versus placebo; most able to stop treatment
via ESC: PCSK9 Drug Dramatically Cuts Apheresis in FH
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CardioBrief: Dollars for Heart Docs

(MedPage Today) -- Last year cardiologists received more than $200 million from industry
via CardioBrief: Dollars for Heart Docs
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ESC: Beta-Blocker Cuts Early Heart Damage from Cancer Tx?

(MedPage Today) -- No clinical difference in small trial, but preclinical measures suggestive
via ESC: Beta-Blocker Cuts Early Heart Damage from Cancer Tx?
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CardioBrief: Cardiologists Give SPRINT Thumbs Down

(MedPage Today) -- Trial should not be used in guidelines to lower blood pressure targets
via CardioBrief: Cardiologists Give SPRINT Thumbs Down
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Sunday, August 28, 2016

ESC: Stent Retriever Therapy OK Without tPA?

(MedPage Today) -- Procedure "may be as similarly effective and safe as bridging thrombolysis"
via ESC: Stent Retriever Therapy OK Without tPA?
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ESC: CPAP Flops for Secondary CV Prevention

(MedPage Today) -- No impact on coronary, stroke risks from sleep apnea tx in SAVE trial
via ESC: CPAP Flops for Secondary CV Prevention
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Saturday, August 27, 2016

PodMed: A Medical News Roundup From Johns Hopkins (with audio)

(MedPage Today) -- This week's topics include breast density and mammography, genetic analysis and chemotherapy in early breast cancer, reducing sugar for kids, and treating essential tremor
via PodMed: A Medical News Roundup From Johns Hopkins (with audio)
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ESC: Continental Divide on Lipid Guidelines

(MedPage Today) -- ESC comes out in favor of LDL targets, no tx if low LDL despite high risk
via ESC: Continental Divide on Lipid Guidelines
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ESC: Afib Guide Boosts Threshold for Treating Women

(MedPage Today) -- New European recommendations change CHA2DS2-VASc score level
via ESC: Afib Guide Boosts Threshold for Treating Women
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Friday, August 26, 2016

Report Ups Fears of Cardiac Device Hacking

(MedPage Today) -- But investment firm's profit motive muddies the water
via Report Ups Fears of Cardiac Device Hacking
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ESC: ICDs for Non-ischemic HF in the Spotlight

(MedPage Today) -- DANISH trial weighs necessity in era of lower mortality, better meds
via ESC: ICDs for Non-ischemic HF in the Spotlight
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Wednesday, August 24, 2016

Wild West of Healthcare: Lab Companies Reeling in the $$$

(MedPage Today) -- In this second part of the 'Billion Dollar Lab Scandal,' Larry Husten offers variations on the theme
via Wild West of Healthcare: Lab Companies Reeling in the $$$
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Xience V Useful for Very Long Lesions (CME/CE)

(MedPage Today) -- No increased risks associated with stenting lesions over 35 mm
via Xience V Useful for Very Long Lesions (CME/CE)
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What Halved PCI Readmits at This Center?

(MedPage Today) -- Possibilities included better patient education, electronic tracking
via What Halved PCI Readmits at This Center?
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SNAP Won't Become Alzheimer's (CME/CE)

(MedPage Today) -- Two studies suggest those with SNAP not likely to progress to Alzheimer's
via SNAP Won't Become Alzheimer's (CME/CE)
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Monday, August 22, 2016

Make the Diagnosis: Questionable Bleeding

(MedPage Today) -- Case Findings: A 19-year-old man presented at the ED vomiting blood. He mentioned that he had several nosebleeds that week, but didn't think anything of it as he frequently suffered from nosebleeds. "It runs in the family. My dad gets them all the time too, he said. Upon exam, his physician noticed an oral red macule on his tongue and slight conjunctival injection. What is your diagnosis?
via Make the Diagnosis: Questionable Bleeding
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Omega-6 in Stored Fat Tied to Longer Survival (CME/CE)

(MedPage Today) -- Slightly lower death rate seen with higher levels in cohort study
via Omega-6 in Stored Fat Tied to Longer Survival (CME/CE)
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Saturday, August 20, 2016

PodMed: A Medical News Roundup From Johns Hopkins (with audio)

(MedPage Today) -- This week's topics include a look at beta blockers, intranasal flu vaccine efficacy, acetaminophen during pregnancy, and a new osteoporosis treatment
via PodMed: A Medical News Roundup From Johns Hopkins (with audio)
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D.C. Week: NOAC Reversal Drug Stalls at FDA

(MedPage Today) -- If Clinton wins the election, what becomes of the Family Foundation?
via D.C. Week: NOAC Reversal Drug Stalls at FDA
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Friday, August 19, 2016

Presidential Candidates' Health at Issue in Election

(MedPage Today) -- Disclosure is needed, but diagnosis from afar is wrong, say experts
via Presidential Candidates' Health at Issue in Election
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Sedentary Advisory; PCSK9 Cost; AEDs After Hours

(MedPage Today) -- Cardiovascular Daily wraps up the top cardiology news of the week
via Sedentary Advisory; PCSK9 Cost; AEDs After Hours
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Thursday, August 18, 2016

Worse MI Outcomes for the Poor? (CME/CE)

(MedPage Today) -- More adverse events after discharge in dual Medicare-Medicaid eligibles
via Worse MI Outcomes for the Poor? (CME/CE)
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Wednesday, August 17, 2016

TAVR Bests Surgery for Survival in Lower-Risk Patients

(MedPage Today) -- Surgery, CoreValve otherwise on par for those with STS PROM below 7%
via TAVR Bests Surgery for Survival in Lower-Risk Patients
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PDUFA Again: Still Trying to Get It Right

(MedPage Today) -- FDA juggles staffing problems with public concerns
via PDUFA Again: Still Trying to Get It Right
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Plavix Smoker's Paradox Debunked? (CME/CE)

(MedPage Today) -- Hemoglobin confounds platelet level readings, study suggests
via Plavix Smoker's Paradox Debunked? (CME/CE)
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Angina Often Under-Recognized in Stable CAD

(MedPage Today) -- Clinicians' lower ratings of frequency could spell undertreatment
via Angina Often Under-Recognized in Stable CAD
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Study: Absorb Stent Works Below the Knee

(MedPage Today) -- "Excellent" results but only in unusually focal lesions
via Study: Absorb Stent Works Below the Knee
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CardioBrief: Can 50 Million Prescriptions Be Wrong?

(MedPage Today) -- Innovative trial to determine actual benefit of hydrochlorothiazide
via CardioBrief: Can 50 Million Prescriptions Be Wrong?
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Monday, August 15, 2016

DASH Diet: A Role in Gout? (CME/CE)

(MedPage Today) -- Large effect size for lowering uric acid
via DASH Diet: A Role in Gout? (CME/CE)
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Sunday, August 14, 2016

Mono/Combo Therapy Improves HDL in Early RA (CME/CE)

(MedPage Today) -- Study hints at new ways to reduce CV risk in arthritis patients
via Mono/Combo Therapy Improves HDL in Early RA (CME/CE)
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Saturday, August 13, 2016

PodMed: A Medical News Roundup From Johns Hopkins (with audio)

(MedPage Today) -- This week's topics include the impact of exercise on chronic medical conditions, more ICU care and outcomes, m-health and diabetes, and insurance status and cancer outcomes
via PodMed: A Medical News Roundup From Johns Hopkins (with audio)
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Friday, August 12, 2016

USPSTF on Kids' Lipids; ICU Overuse; BP Variability

(MedPage Today) -- Cardiovascular Daily wraps up the top cardiology news of the week
via USPSTF on Kids' Lipids; ICU Overuse; BP Variability
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Morning Break: Dying to Make a Sale; Neuros vs NYT; Hookup Apps

(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff
via Morning Break: Dying to Make a Sale; Neuros vs NYT; Hookup Apps
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Wednesday, August 10, 2016

Survival Advantage With Extended DAPT After MI?

(MedPage Today) -- Updated meta-analysis enters the fray over antiplatelet duration
via Survival Advantage With Extended DAPT After MI?
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Long-Term Warfarin Stability Elusive

(MedPage Today) -- Registry challenges common reason for not switching to NOACS
via Long-Term Warfarin Stability Elusive
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Make the Diagnosis: Dizziness Dilemma

(MedPage Today) -- Case Findings: A 42-year-old African American male presents with a report of dizziness and lightheadedness 3 days ago when he was standing up to go to the rest room. He denies any syncopal episodes. He has medically managed hypertension, hypercholesterolemia, and cardiomyopathy, and a last ejection fraction of 35% with defibrillator placement 4 months ago. His AICD did not fire during the dizziness episode. His last cardiac catheterization prior to AICD implantation revealed normal coronaries. The patient has been compliant with metoprolol 25 mg twice daily, lisinopril 10 mg daily, atorvastatin 40 mg daily. He denies any new medical regimen. His vital signs are BP 100/80 mm Hg and HR 66/min. His physical examination is normal without any clinical evidence of decompensation. What is best course of action based on what the ECG suggests?
via Make the Diagnosis: Dizziness Dilemma
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ATS Report: Tighten Air Quality Standards to Save Lives

(MedPage Today) -- More than 9,000 deaths, 21,000 nonfatal events preventable annually
via ATS Report: Tighten Air Quality Standards to Save Lives
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Tuesday, August 9, 2016

MondoA May Be T2D Drug Target

(MedPage Today) -- Mouse studies show promise for inhibitors
via MondoA May Be T2D Drug Target
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Monday, August 8, 2016

USPSTF: No Data on Lipid Screening of Young Adults

(MedPage Today) -- Extrapolation necessary on screening, treatment before age 40
via USPSTF: No Data on Lipid Screening of Young Adults
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FDA Commissioner: Cardiology Can Do Better

(MedPage Today) -- Califf calls on field to modernize evidence development
via FDA Commissioner: Cardiology Can Do Better
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Intracoronary Abciximab Better for Diabetics? (CME/CE)

(MedPage Today) -- Meta-analysis suggests big advantage, but some call it implausible
via Intracoronary Abciximab Better for Diabetics? (CME/CE)
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CardioBrief: Trialists Dig In

(MedPage Today) -- Shrinking from the sunlight of data-sharing
via CardioBrief: Trialists Dig In
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Saturday, August 6, 2016

Wednesday, August 3, 2016

CardioBrief: Mixed Support For Data Sharing

(MedPage Today) -- Many top investigators seek to weaken existing proposals
via CardioBrief: Mixed Support For Data Sharing
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High BMI Tied to T2D, but Not to Heart Troubles (CME/CE)

(MedPage Today) -- Twin study suggests causal link between obesity and diabetes risk, independent of genetics
via High BMI Tied to T2D, but Not to Heart Troubles (CME/CE)
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Medicare $$ Up for Cardiology in 2017

(MedPage Today) -- Mitral repair, LAA closure get big bump in finalized fee schedule
via Medicare $$ Up for Cardiology in 2017
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Insomnia, Snoring Linked to Stroke (CME/CE)

(MedPage Today) -- Review shows independent predictors beforehand, high prevalence afterward
via Insomnia, Snoring Linked to Stroke (CME/CE)
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Fish Oil May Improve Post-MI Recovery (CME/CE)

(MedPage Today) -- Inflammation, fibrosis, remodeling reduced in clinical trial
via Fish Oil May Improve Post-MI Recovery (CME/CE)
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Tuesday, August 2, 2016

CoreValve Cleared For Lower-Risk TAVR In Europe

(MedPage Today) -- Clinicians eye a similar expansion for TAVR in the U.S.
via CoreValve Cleared For Lower-Risk TAVR In Europe
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The Big Dirty Secret Every Doctor Knows

(MedPage Today) -- Eminence-based medicine is not the exception. It's the rule.
via The Big Dirty Secret Every Doctor Knows
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Off-Site Cardiac Monitor Boosts Non-ICU Telemetry

(MedPage Today) -- Program improved accuracy of notification, patient selection
via Off-Site Cardiac Monitor Boosts Non-ICU Telemetry
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Make the Diagnosis: Athletic or At Risk?

(MedPage Today) -- Case Findings: A 32-year-old athletic female presents for a general medical examination. She does not have any known medical diagnoses. She runs 5 miles a day. Recently, while she was exercising at the gym, she had an episode of lightheadedness. She reports no similar prior episodes. She does mention that it was a hot, sunny day and she had worked out much more than usual. She denies any chest pain, palpitations, or syncopal episodes. One of her cousins is studying in medical school and did quick vitals on her. He was concerned that her heart rate was consistently in low 50s, and he suggested that she be checked at a medical clinic for further workup. Her EKG is shown. Which of the following is true?
via Make the Diagnosis: Athletic or At Risk?
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Study: For Long Life, Chose Beans Over Burgers (CME/CE)

(MedPage Today) -- Plant protein-heavy diets linked to lower mortality in observational data
via Study: For Long Life, Chose Beans Over Burgers (CME/CE)
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Benign Adrenal Tumors Linked to Diabetes Risk (CME/CE)

(MedPage Today) -- "Non-functional tumors may secrete small but problematic levels of glucocorticoids
via Benign Adrenal Tumors Linked to Diabetes Risk (CME/CE)
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Pearls From: John Laird

(MedPage Today) -- An interventional cardiologist discusses peripheral artery disease
via Pearls From: John Laird
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Monday, August 1, 2016